PGD: fertility treatment for prospective parents with a hereditary condition

PGD is a special treatment for people who want children and also have a genetic disorder.

How does PGD work?

If you run the risk of passing on a hereditary disorder to your child, you can first perform a prenatal test. These tests are invasive meaning they take material (tissue or fluid) from the fetus, uterus or placenta.

Embryos obtained via in vitro fertilization (IVF) are diagnosed genetically in the laboratory first. Only the unaffected embryos, without genetic defect, may be implanted in the uterus. Therefore, PGD can be regarded as a very early prenatal diagnosis.

First step: preliminary examinations

It’s important to know which genetic defect we are looking for, it might be a defect in the chromosomes or in one particular gene. So it’s necessary to have sufficient information about the disorder so a customized PGD test can be developed.

In addition to the preliminary examinations it’s also necessary to first have consultations with the genetics doctor and the fertility gynecologist. Only after these consultations, the team will decide if PGD treatment is possible and how your treatment will proceed.

If these tests or consultations were to indicate that you are not eligible for PGD, the entire procedure will be put on hold.

Only for genetic diseases whose defect is known.

We can provide genetic analysis of embryos for all monogenetic diseases whose genetic defect is known.

Some examples:

  • Cystic fibrosis
  • Sickle cell anaemia
  • Steinert’s disease (myotonic dystrophy)
  • Huntington’s disease
  • Marfan syndrome
  • Neurofibromatosis type I and type II
  • Duchenne muscular dystrophy
  • Fragile X syndrome
  • Haemophilia A

Fertility Belgium - PGD treatment

Reproductive treatment

  1. Analysis of the results with the fertility gynecologist and the genetics doctor
  2. Counselling by the fertility doctor
  3. Schedule the appointments
  4. Ovarian stimulation
  5. Egg retrieval
  6. IVF/ICSI fertilization in the lab, including embryo biopsy and genetic diagnosis of the embryos
  7. Embryo transfer: one or several unaffected embryo(s) in the current or following cycle
  8. Freezing all or surplus embryos in the lab
  9. If successful: monitoring of early pregnancy
    If not pregnant: transfer of thawed embryos or start a new IVF/ICSI cycle

More information about ICSI procedure

Travelling for the consultations and during the treatment

For foreign patients we try to keep the travelling to a minimum and combine several consultations. The ovarian stimulation during the first phase of the treatment can be done while you’re at home.

For the egg retrieval and the transfer of the embryo(s) you do have to come to the hospital for a couple of hours each time.

In Belgium, PGD has been applied since the beginning of 1993

Belgium has expanded to become one of the leading fertility centers in Europe. Postnatal follow-up is an important part of the treatment. As one of the few countries in the world, Belgium has consistently monitored all babies born of PGD treatment. With this scientific research we are at the absolute top.

Please note that the best method of treatment always depends on the nature of your fertility problem. Therefore a fertility specialist must first review your medical file.

Fertility Belgium is the shortest way to the best care in Belgium. Thanks to our know-how we can connect you to the best doctors for your treatment. Contact us for more details and access to the best fertility clinics in Belgium.

Do you have any question about IVM, IVF, ICSI, artificial insemination, insemination by donor or other fertility treatments?

Feel free to contact us by phone (+32 51 67 67 60) or mail.
You can use the contact form or just send us an e-mail to info@fertilitybelgium.be.
We will give you an answer within 24 hours.

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